NFL Week 12 Picks on the San Diego Chargers vs Indianapolis Colts Betting Odds: The Indianapolis Colts host the again-resurgent San Diego Chargers, Sunday Nov 28, as the Chargers try for their fourth straight win and the Colts try to keep their perfect home record intact. The Chargers won their last meeting 23-17 (OT), at home, in 2009. NFL oddsmakers at SPORTSBOOK.com have the Colts as -3 point home favorites over the Chargers while the game’s total has been posted at 51.5 points. Be sure to get the latest NFL Spreads for your NFL Week 12 Picks on the San Diego Chargers vs Indianapolis Colts Betting Odds.

The Chargers (5-5) (1-4 V) beat Denver 35-14, at home, in Week 11 and sit tied for second in the AFC West, with Oakland. QB Phillip Rivers made 15 of 24 passes for 233 yards with four TD’s and an interception. RB Michael Tolbert had 25 carries for 111 yards with a TD, while WR Patrick Crayton made three catches for 105 yards with a TD. RB Darren Sproles made five catches for 60 yards with a TD; Malcom Floyd and Jacob Hester each added a TD. The Chargers have won eight consecutive November games. Their defense had five sacks and one interception. Philip Rivers can match Peyton Manning when it comes to driving an offense through the air, so it seems a certainty this will be a shootout. The game within the game could be turnovers because while San Diego is approaching prolific levels with Rivers slinging it around, the Chargers have 22 giveaways. The Colts typically take care of the football with just 13 giveaways, but the highlights all week have been of Manning throwing three INTs to the Patriots. The Chargers will look to rattle Manning with their blitzes, playing the chess game of dropping back into coverage at times to look for interceptions. The Chargers offense is ranked best overall (418ypg) with the best ranked pass game (306ypg) and a 17th ranked running game (111ypg). They score the third most amount of points per-game (27.4ppg). Antonio Gates leads their offense with nine TD’s. The Chargers go up against the Colts 20th ranked defense (344ypg), their eighth ranked pass rush (207ypg) and their 30th ranked rush defense (136ypg). The Colts give up the 15th most amount of points per-game (21.6ppg).

The Colts (6-4) (4-0 H) lost in New England 28031, in Week 11 and sit tied for first in the AFC South, with Jacksonville.  QB Peyton Manning made 38 of 52 passes for 396 yards with four TD’s and three interceptions. RB Donald Brown had 17 carries for 68 yards, while WR Reggie Wayne made eight catches for 107 yards with a TD. Blair White had two TD’s and Gijon Robinson had one TD. Their defense managed one sack and no interceptions. WR Austin Collie has been ruled out for Sundays game after he encountered symptoms related to a concussion sustained Nov. 7. RB Joseph Addai, who has missed the past four games with a shoulder injury, is expected to participate in non-contact practice drills for conditioning purposes this week. A timetable for a full return is uncertain, the team said. The Colts will look to generate a pass rush with defensive ends Dwight Freeney and Robert Mathis as well as the timely blitz or Rivers will carve up a secondary which often backs off and gives too much cushion to receivers. The Colts offense is ranked fourth best overall (388ypg) with the second best ranked pass game (299ypg) and a 27th ranked running game (88ypg). They score the fourth highest amount of points per-game (26.8ppg). Austin Collie leads their offense with six TD’s. The Colts battle the Chargers first ranked defense (270ypg), their first ranked pass rush (183ypg) and the NFL’s third best ranked rush defense (86ypg). The Chargers give up the 14th most amount of points per-game (21.1ppg).

Recent Trends to Consider:  

  • Chargers are 5-1 ATS in their last 6 meetings.
  • Chargers are 5-1 ATS in their last 6 meetings in Indianapolis.
  • Under is 4-1 in the last 5 meetings.
  • Road team is 5-2 ATS in their last 7 meetings.
  • Underdog is 7-0 ATS in their last 7 meetings.
  • Chargers are 1-4 ATS in their last 5 road games.
  • Colts are 5-1-1 ATS in their last 7 games in November.
  • Colts are 4-1-1 ATS in their last 6 games overall.

San Diego Chargers vs Indianapolis Colts
When: Sun, Nov 28, 8:20 PM ET
Line:  SPORTSBOOK.com
Pick: Colts -3

Point-Spreads.com recommends you get your NFL Picks Week 12 in early!

The Bottom Line: Peyton at home, is a beautiful thing. Be sure to get your NFL Week 12 Picks: San Diego Chargers vs Indianapolis Colts Betting Odds in now at SPORTSBOOK.com